96% reported improvement in premenstrual symptoms: inside Evelyn’s 90-day Consumer Study

Why we ran a consumer study on PMS and PMDD symptoms

For many women, PMS and PMDD are still framed as something to tolerate - mood swings, fatigue, irritability, anxiety, pain.

But premenstrual symptoms rarely appear in isolation. They can affect sleep, productivity, relationships and overall wellbeing. Many women describe feeling like a different version of themselves for part of every month.

Despite how common this experience is, there is still a surprising lack of structured, real-world data on interventions designed to support cycle health.

That is why we conducted a 90-day consumer study with women using Evelyn consistently across multiple menstrual cycles. Our aim was simple: to understand whether women experienced meaningful changes in their symptoms over time.

Not in theory, and not in a laboratory setting - but in everyday life.

 

How the 90-day study worked

The study followed women who had been using Evelyn for at least three months, allowing us to assess changes across multiple cycles.

Participants completed a structured questionnaire covering emotional, cognitive and physical symptoms associated with PMS and PMDD. Symptoms were assessed using a framework aligned with the Daily Record of Severity of Problems (DRSP)*, a validated symptom tracking method widely used in research on PMS and PMDD.

The study included:

• 85 women / people who menstruate
• A minimum of 90 days of consistent use
• Structured symptom reporting across multiple cycles
• Symptom assessment aligned with the DSRP framework

This was a real-world consumer study, not a placebo-controlled clinical trial. To date, no supplement brand has conducted a placebo-controlled clinical trial evaluating a combined supplement routine for PMS or PMDD.

Most placebo-controlled research in this field has focused on individual ingredients, rather than the multi-ingredient routines women often use in practice to support different aspects of the cycle.

Real-world studies like this help begin to address that gap by capturing how women actually experience symptom change across multiple cycles. Over time, Evelyn intends to help raise the standard of evidence in this area - including supporting future placebo-controlled research on combined approaches to premenstrual health.

 

The headline findings

Across the study, women reported meaningful improvements in their symptoms over time.

96% reported an overall improvement in symptom severity after three months.

Many women also noticed changes earlier.

65% reported improvement within the first month of use.

For something as complex as premenstrual health, this matters. PMS and PMDD are not single symptoms that can be switched off overnight. They are a whole-body response to hormonal changes that can influence emotional wellbeing, cognition, energy, sleep and physical comfort.

To understand these changes more clearly, we also looked at where women reported improvement across different areas of daily life.

 

PMS and PMDD affect the whole body

Research has linked more than 150 symptoms to PMS and PMDD. These symptoms span emotional wellbeing, cognitive function, sleep, digestion, physical discomfort and behavioural changes.

To better understand how women experience these changes, Evelyn groups premenstrual symptoms into nine core areas of cycle health.

Women in the study reported improvements across every symptom category.

Mood and emotional wellbeing

96% reported fewer mood swings or reduced emotional sensitivity.

 

Focus and motivation

79% reported improved concentration and productivity.

Calm and stress regulation

96% reported feeling less anxious, tense or on edge.

 

Energy and fatigue

81% reported feeling less tired or lacking in energy.

 

Sleep and rest

69% reported improved sleep patterns.

 

Physical comfort

71% reported reduced bloating, breast tenderness, headaches or muscle pain.

 

Appetite and cravings

56% reported reduced appetite disruption or fewer food cravings.

 

Social and relationship wellbeing

87% reported their symptoms interfered less with relationships.

 

Overall sense of wellbeing

90% reported feeling less overwhelmed or out of control.

Premenstrual symptoms do not just affect how women feel. They affect how women live, work and relate to others. Seeing improvements across multiple areas of life highlights the importance of supporting the cycle as a whole system, rather than focusing on individual symptoms alone.

 

What this study was - and what it wasn't. 

This research represents structured real-world evidence from women using Evelyn over multiple cycles.

It provides insight into how women report changes in their symptoms when using the product consistently over time.

However, it is important to note that this was not a placebo-controlled clinical trial. Consumer studies capture lived experience and real-world outcomes, but they should be interpreted alongside clinical research and ongoing investigation.

At Evelyn, we believe transparency matters - particularly in women’s health, where reliable data has historically been limited.

 

What happens next?

This study is the first step in building a stronger evidence base for premenstrual health.

A full report of the 90-day consumer study, including methodology, symptom analysis and detailed findings, will be published on the Evelyn website shortly.

Our goal is simple: raise the standard of evidence in a category that has historically been overlooked.

Because when it comes to PMS, PMDD and cycle health, women deserve clear information, transparent research and better solutions.

* DRSP (Daily Record of Severity of Problems) is a clinically validated symptom-tracking tool commonly used in research on PMS and PMDD to assess changes in emotional and physical symptoms across the menstrual cycle.